GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs9902453 | 1 | rs4795525 | chr17:28388487 | EFCAB5 | chr17:28256874-28435469:+ | -0.4 | -5.08 | 4.7E-6 | Coffee consumption (cups per day) |
| UVM | cis | rs2273 | 1 | rs4859413 | chr4:76898250 | NAAA | chr4:76831809-76862166:- | 0.47 | 5.35 | 1.77E-6 | Longevity |
| UVM | cis | rs2273 | 1 | rs4859581 | chr4:76906974 | NAAA | chr4:76831809-76862166:- | -0.43 | -4.84 | 1.07E-5 | Longevity |
| UVM | cis | rs2273 | 1 | rs4859582 | chr4:76907213 | NAAA | chr4:76831809-76862166:- | -0.44 | -4.99 | 6.33E-6 | Longevity |
| UVM | cis | rs4869313 | 1 | rs4869313 | chr5:96223880 | ERAP2 | chr5:96211644-96255398:+ | -0.81 | -7 | 3.7E-9 | Pediatric autoimmune diseases |
| UVM | cis | rs11148252 | 1 | rs4886018 | chr13:52990717 | NEK3 | chr13:52706780-52733996:- | 0.46 | 5.76 | 3.94E-7 | Lewy body disease |
| UVM | cis | rs2239557 | 1 | rs4903201 | chr14:74659690 | LIN52 | chr14:74551656-74667117:+ | -0.44 | -5.65 | 5.92E-7 | Common traits (Other) |
| UVM | cis | rs2239557 | 1 | rs4903202 | chr14:74660302 | LIN52 | chr14:74551656-74667117:+ | -0.44 | -5.65 | 5.92E-7 | Common traits (Other) |
| UVM | cis | rs2239557 | 1 | rs4903203 | chr14:74660508 | LIN52 | chr14:74551656-74667117:+ | -0.44 | -5.65 | 5.92E-7 | Common traits (Other) |
| UVM | cis | rs11190604 | 1 | rs4917901 | chr10:102201773 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs4919464 | chr10:102221195 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs4919465 | chr10:102221703 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs4919466 | chr10:102241213 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs4919468 | chr10:102288343 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs4919469 | chr10:102298855 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |